Unit 6: Clinical Trials

Overview

Drug Development & Clinical Trials

The Patient Perspective

The Drug Development Process

Clinical Trials by the Numbers

What is a Randomized Clinical Trial?

Why Do We Need to Randomize?

Trial Design

Statistical Framework for Clinical Trials

Balanced Two-Arm RCT

Type I vs. Type II Errors

Cost vs. Type I & Type II Errors

Changing the Threshold c

Formal Statistical Analysis

Hypothesis Testing Review

Alternative Hypothesis vs. Power

Bayesian Adaptive Clinical Trials

Adaptive Designs

The Role of Behavior

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